Lipophytol® (Microencapsulated Plant Sterols — Lipofoods)

Evidence Level
Strong
1 Clinical Trial
3 Documented Benefits
4/5 Evidence Score

Lipophytol® is a water-dispersible, microencapsulated plant sterol ingredient from Lipofoods (a Lubrizol company). Microencapsulation lets these cholesterol-lowering plant sterols mix easily into foods and supplements. Plant sterols are among the best-established ingredients for lowering LDL cholesterol.

Studied Dose About 1.5 to 3 grams of plant sterols per day with meals.
Active Compound Microencapsulated, water-dispersible plant sterols (phytosterols), up to 90% sterol content.

Benefits

Lower LDL cholesterol

Plant sterols at about 1.5 to 3 grams per day lower LDL (bad) cholesterol by roughly 8 to 15%, a benefit recognized by regulators and reviews.

Cardiovascular prevention

By lowering LDL cholesterol, plant sterols support long-term cardiovascular health as part of a heart-healthy diet.

Easy formulation

Microencapsulation makes the normally hard-to-use sterols water-dispersible, so they blend smoothly into drinks and foods.

Mechanism of action

1

Blocked cholesterol absorption

Plant sterols compete with cholesterol for uptake in the intestine, reducing how much dietary and biliary cholesterol is absorbed.

2

Increased LDL clearance

Lower absorption prompts the liver to pull more LDL cholesterol from the blood.

Clinical trials

1
Plant Sterols and Cholesterol — Evidence Review
PubMed

Review of plant sterols and stanols in cholesterol management and cardiovascular prevention. (Barkas et al. 2023, Nutrients)

Adults across the evidence base.

About 2 grams per day of plant sterols consistently lowered LDL cholesterol, supporting cardiovascular prevention.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated at recommended intakes.
May slightly lower absorption of fat-soluble vitamins and carotenoids; eat plenty of produce.
Mild digestive upset is occasionally reported.

Important Drug interactions

Ezetimibe — both reduce cholesterol absorption; consult your doctor.
Plant sterols complement statins; tell your doctor you use them.
People with sitosterolemia should avoid plant sterols.

Frequently asked questions about Lipophytol® (Microencapsulated Plant Sterols — Lipofoods)

What is Lipophytol?

Lipophytol® is a water-dispersible, microencapsulated plant sterol ingredient from Lipofoods (a Lubrizol company). Microencapsulation lets these cholesterol-lowering plant sterols mix easily into foods and supplements. Plant sterols are among the best-established ingredients for lowering LDL cholesterol.

What is Lipophytol used for?

Lipophytol is researched primarily for Cardiovascular. Plant sterols at about 1.5 to 3 grams per day lower LDL (bad) cholesterol by roughly 8 to 15%, a benefit recognized by regulators and reviews.

What is the recommended dosage of Lipophytol?

The clinically studied dose is About 1.5 to 3 grams of plant sterols per day with meals. Always follow the product label and check with a healthcare provider for personal advice.

Is Lipophytol safe, and does it have side effects?

For most healthy adults, Lipophytol is well tolerated at studied doses. Reported effects can include: Generally well-tolerated at recommended intakes. May slightly lower absorption of fat-soluble vitamins and carotenoids; eat plenty of produce. It may also interact with some medications. Lipophytol is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does Lipophytol interact with any medications?

Possible interactions include: Ezetimibe — both reduce cholesterol absorption; consult your doctor. Plant sterols complement statins; tell your doctor you use them. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for Lipophytol?

NutraSmarts rates the evidence for Lipophytol as Strong (4 out of 5). It is backed by 1 clinical trial and 1 cited reference summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Barkas F, Bathrellou E, Nomikos T, et al. Plant Sterols and Plant Stanols in Cholesterol Management and Cardiovascular Prevention. Nutrients. 2023;15(13). doi: 10.3390/nu15132845..PubMedUsed to support: Review supporting LDL-cholesterol lowering by plant sterols (the active in Lipophytol).