Go-Less® (Pumpkin Seed and Soybean Germ Extract)

Cucurbita pepo
Evidence Level
Moderate
1 Clinical Trial
3 Documented Benefits
3/5 Evidence Score

Go-Less® combines pumpkin seed extract with soybean germ extract to support bladder control. Pumpkin seed has traditional use for urinary health, and clinical research on pumpkin seed found improvements in overactive-bladder symptoms, the basis for Go-Less as a natural bladder-support ingredient.

Studied Dose Commonly around 500 mg per day of the combined extract.
Active Compound Pumpkin seed (Cucurbita pepo) extract combined with soybean germ extract.

Benefits

Bladder control

A clinical study of pumpkin seed found improvement in overactive-bladder symptoms, supporting Go-Less for healthy bladder control and reduced urinary urgency.

Urinary comfort

Pumpkin seed is traditionally used to support comfortable, normal urinary function in both women and men.

Pelvic-floor support

The soybean germ component contributes isoflavones thought to support the tissues involved in bladder control.

Mechanism of action

1

Bladder-muscle support

Pumpkin seed compounds are thought to support healthy tone and function of the bladder and surrounding muscles, easing urgency and frequency.

2

Isoflavone support

Soybean germ isoflavones provide gentle hormone-like support to the pelvic and urinary tissues.

Clinical trials

1
Pumpkin Seed and Overactive Bladder — Clinical Study
PubMed

Clinical study of pumpkin seed oil on urinary disorder in human overactive bladder. (Nishimura et al. 2014, Journal of Traditional and Complementary Medicine)

Adults with overactive-bladder symptoms.

Pumpkin seed oil improved overactive-bladder symptom measures, supporting the bladder-control positioning.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated — adverse effects are uncommon at normal doses.
Mild digestive upset is occasionally reported.
Discontinue if any unusual reaction occurs.

Important Drug interactions

Soy allergy — this ingredient contains soybean germ; avoid if allergic.
Hormone-sensitive conditions — consult a doctor about the soy isoflavones.
Tell your doctor about persistent urinary symptoms to rule out other causes.

Frequently asked questions about Go-Less® (Pumpkin Seed and Soybean Germ Extract)

What is Go-Less?

Go-Less® combines pumpkin seed extract with soybean germ extract to support bladder control. Pumpkin seed has traditional use for urinary health, and clinical research on pumpkin seed found improvements in overactive-bladder symptoms, the basis for Go-Less as a natural bladder-support ingredient.

What is Go-Less used for?

Go-Less is researched primarily for Kidney/Urinary Tract, Women's Health, and Men's Health. A clinical study of pumpkin seed found improvement in overactive-bladder symptoms, supporting Go-Less for healthy bladder control and reduced urinary urgency.

What is the recommended dosage of Go-Less?

The clinically studied dose is Commonly around 500 mg per day of the combined extract. Always follow the product label and check with a healthcare provider for personal advice.

Is Go-Less safe, and does it have side effects?

For most healthy adults, Go-Less is well tolerated at studied doses. Reported effects can include: Generally well-tolerated — adverse effects are uncommon at normal doses. Mild digestive upset is occasionally reported. It may also interact with some medications. Go-Less is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does Go-Less interact with any medications?

Possible interactions include: Soy allergy — this ingredient contains soybean germ; avoid if allergic. Hormone-sensitive conditions — consult a doctor about the soy isoflavones. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for Go-Less?

NutraSmarts rates the evidence for Go-Less as Moderate (3 out of 5). It is backed by 1 clinical trial and 1 cited reference summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Nishimura M, Ohkawara T, Sato H, et al. Pumpkin Seed Oil Extracted From Cucurbita maxima Improves Urinary Disorder in Human Overactive Bladder. J Tradit Complement Med. 2014;4(1):72-4..PubMedUsed to support: Clinical study supporting bladder-control benefit of pumpkin seed.