GinPure® (Ginkgo biloba Extract)

Ginkgo biloba
Evidence Level
Moderate
1 Clinical Trial
3 Documented Benefits
3/5 Evidence Score

GinPure® is a purified, standardized Ginkgo biloba leaf extract concentrated for flavone glycosides and terpene lactones. Ginkgo has been studied mainly in older adults with cognitive impairment or dementia, and traditionally for circulation; the RCT-validated extract is EGb761 rather than GinPure specifically.

Studied Dose Commonly 120 to 240 mg of standardized extract per day.
Active Compound Ginkgo biloba leaf extract, standardized to about 24% flavone glycosides and 6% terpene lactones.

Benefits

Cognition and memory

In the cited meta-analysis (Tan 2015), standardized Ginkgo biloba extract supported cognition and daily function specifically in older adults with cognitive impairment or dementia. Large prevention trials in healthy elderly (GEM, GuidAge) found no benefit, and memory enhancement in healthy adults is not well established. Most of this evidence comes from the EGb761 extract rather than GinPure specifically. This statement has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease.

Circulation

Ginkgo supports healthy blood flow, including to the brain and extremities, part of its traditional use.

Antioxidant support

Ginkgo flavonoids provide antioxidant protection for brain and blood-vessel tissue.

Mechanism of action

1

Microcirculation support

Ginkgo's flavone glycosides and terpene lactones support blood-vessel function and healthy circulation to the brain and periphery.

2

Antioxidant neuroprotection

Ginkgo antioxidants protect neurons and blood vessels from oxidative stress, supporting cognitive function.

Clinical trials

1
Ginkgo biloba and Cognition — Meta-Analysis
PubMed

Systematic review and meta-analysis of Ginkgo biloba for cognitive impairment and dementia. (Tan et al. 2015, Journal of Alzheimer's Disease)

Adults with cognitive impairment across trials.

Ginkgo biloba extract supported cognition and daily function in cognitively impaired adults, with a good safety profile.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated.
Mild headache or digestive upset can occur.
Rarely, mild dizziness.

Important Drug interactions

Anticoagulants and antiplatelets — ginkgo may increase bleeding risk; monitor.
Seizure disorders — use caution and consult a doctor.
Stop before surgery and tell your doctor.

Frequently asked questions about GinPure® (Ginkgo biloba Extract)

What is GinPure?

GinPure® is a purified, standardized Ginkgo biloba leaf extract concentrated for flavone glycosides and terpene lactones. Ginkgo has been studied mainly in older adults with cognitive impairment or dementia, and traditionally for circulation; the RCT-validated extract is EGb761 rather than GinPure specifically.

What is GinPure used for?

GinPure is researched primarily for Cognitive and Cardiovascular. In the cited meta-analysis (Tan 2015), standardized Ginkgo biloba extract supported cognition and daily function specifically in older adults with cognitive impairment or dementia.

What is the recommended dosage of GinPure?

The clinically studied dose is Commonly 120 to 240 mg of standardized extract per day. Always follow the product label and check with a healthcare provider for personal advice.

Is GinPure safe, and does it have side effects?

For most healthy adults, GinPure is well tolerated at studied doses. Reported effects can include: Generally well-tolerated. Mild headache or digestive upset can occur. It may also interact with some medications. GinPure is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does GinPure interact with any medications?

Possible interactions include: Anticoagulants and antiplatelets — ginkgo may increase bleeding risk; monitor. Seizure disorders — use caution and consult a doctor. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for GinPure?

NutraSmarts rates the evidence for GinPure as Moderate (3 out of 5). It is backed by 1 clinical trial and 1 cited reference summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Tan MS, Yu JT, Tan CC, et al. Efficacy and adverse effects of ginkgo biloba for cognitive impairment and dementia: a systematic review and meta-analysis. J Alzheimers Dis. 2015;43(2):589-603..PubMedUsed to support: Meta-analysis of Ginkgo biloba extract for cognitive impairment and dementia (modest benefit); the trials used the EGb761 extract, a class relative of this branded ginkgo, not GinPure specifically.