Home Ingredients Cynatine® FLX (Solubilized Keratin — Roxlor)
Joint Health

Cynatine® FLX (Solubilized Keratin — Roxlor)

Evidence Level
Moderate
1 Clinical Trial
3 Documented Benefits
3/5 Evidence Score

Cynatine® FLX is a solubilized, bioavailable keratin from Roxlor, formulated for joint support. Keratin is a sulfur-rich structural protein, and the solubilized form is studied for easing joint discomfort and supporting flexibility, with a randomized, placebo-controlled trial behind it.

Studied Dose About 500 mg per day.
Active Compound Solubilized keratin, a bioavailable form of the sulfur-rich structural protein, standardized for joint support.

Benefits

Joint comfort and flexibility

In a randomized, placebo-controlled trial, solubilized keratin supported reductions in joint discomfort and improvements in flexibility and range of motion.

Supported by Trial 1

Connective-tissue protein

Keratin supplies sulfur amino acids used in connective tissue, supporting the maintenance of joint and cartilage structures.

Supported by Trial 1

Antioxidant sulfur support

The sulfur in keratin supports the body's antioxidant systems, relevant to the oxidative stress involved in joint discomfort.

Supported by Trial 1

Mechanism of action

1

Sulfur amino acid delivery

Solubilized keratin provides bioavailable cysteine and other sulfur amino acids used to build and maintain connective tissue and antioxidant molecules.

2

Anti-inflammatory support

Keratin supplementation is studied for lowering joint inflammatory markers, contributing to its comfort benefit.

Clinical trials

1
Solubilized Keratin and Joint Health — RCT
PubMed

Randomized, double-blind, placebo-controlled trial of solubilized keratin for joint health. (Beer et al. 2013, Journal of Dietary Supplements)

Adults with joint discomfort.

Solubilized keratin supported reductions in joint pain and improvements in flexibility and range of motion versus placebo.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated — adverse events in the trial were minimal.
Mild digestive upset is occasionally reported.
No known major safety concerns at studied doses.

Important Drug interactions

No significant drug interactions are established.
Generally compatible with other joint supplements.
Tell your doctor if you take medication for arthritis.

More Joint Health Ingredients

Joint Health
Curcuwin Ultra+® (144× Bioavailable Curcumin — OmniActive)
Curcuwin Ultra+® is OmniActive's highly bioavailable curcumin — distinguished by 144× grea…
Joint Health
NEM® (Natural Eggshell Membrane — ESM Technologies)
NEM® is the branded standardized natural eggshell membrane developed by ESM Technologies (…
Joint Health
Undenatured Type II Collagen
Undenatured Type II Collagen (sometimes abbreviated UC-2 or native Type II collagen) is a…
Joint Health
Dynagenix® (Water-Soluble Boswellia for Joint + Muscle Recovery — PLT Health)
Dynagenix® is PLT Health Solutions' next-generation water-soluble, neutral-tasting Boswell…

Explore Other Ingredients

Energy
SalidroPure™ (Pure Salidroside)
SalidroPure™ is NNB Nutrition's precision-fermented pure salidroside — the primary bioacti…
Cognitive
Suntheanine®
Suntheanine® is a patented, 100% pure L-isomer theanine produced via an enzymatic process…
Cognitive
L-Theanine
L-Theanine, an amino acid primarily found in green tea (Camellia sinensis), is commonly su…

Frequently asked questions about Cynatine® FLX (Solubilized Keratin — Roxlor)

What is Cynatine FLX?

Cynatine® FLX is a solubilized, bioavailable keratin from Roxlor, formulated for joint support. Keratin is a sulfur-rich structural protein, and the solubilized form is studied for easing joint discomfort and supporting flexibility, with a randomized, placebo-controlled trial behind it.

What is Cynatine FLX used for?

Cynatine FLX is researched primarily for Joint Health. In a randomized, placebo-controlled trial, solubilized keratin supported reductions in joint discomfort and improvements in flexibility and range of motion.

What is the recommended dosage of Cynatine FLX?

The clinically studied dose is About 500 mg per day. Always follow the product label and check with a healthcare provider for personal advice.

Is Cynatine FLX safe, and does it have side effects?

For most healthy adults, Cynatine FLX is well tolerated at studied doses. Reported effects can include: Generally well-tolerated — adverse events in the trial were minimal. Mild digestive upset is occasionally reported. It may also interact with some medications. Cynatine FLX is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does Cynatine FLX interact with any medications?

Possible interactions include: No significant drug interactions are established. Generally compatible with other joint supplements. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for Cynatine FLX?

NutraSmarts rates the evidence for Cynatine FLX as Moderate (3 out of 5). It is backed by 1 clinical trial and 1 cited reference summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Beer C, Wood S, Veghte RH. A randomized, double-blind, placebo-controlled clinical trial to investigate the effect of cynatine FLX on joint health. J Diet Suppl. 2013;10(3):184-94..PubMedUsed to support: RCT showing joint comfort and flexibility benefit.