Home Ingredients Cucurbidiol® (Pumpkin Seed Oil — Cucurbita)
Prostate HealthMen's HealthKidney/Urinary Tract

Cucurbidiol® (Pumpkin Seed Oil — Cucurbita)

Cucurbita pepo
Evidence Level
Limited
1 Clinical Trial
3 Documented Benefits
2/5 Evidence Score

Cucurbidiol® is a pumpkin seed (Cucurbita) oil ingredient, rich in phytosterols, zinc, and fatty acids traditionally used for prostate and urinary health. Pumpkin seed oil is studied for supporting comfortable urinary flow in men and is also used for hair support.

Studied Dose Commonly around 500 mg to 1 g of pumpkin seed oil per day.
Active Compound Pumpkin seed (Cucurbita pepo) oil rich in phytosterols, fatty acids, and zinc.

Benefits

Prostate and urinary support

Pumpkin seed oil is studied for supporting comfortable urinary flow and easing the urinary symptoms linked to an aging prostate.

Supported by Trial 1

Bladder support

Research found pumpkin seed improved overactive-bladder symptoms, supporting healthy bladder function.

Supported by Trial 1

Hair support

Pumpkin seed oil is also used to support hair, thought to relate to its effect on hormone-related pathways.

Supported by Trial 1

Mechanism of action

1

Phytosterol action

Pumpkin seed phytosterols are thought to support healthy prostate and urinary function, in part through effects on hormone metabolism.

2

Bladder-tone support

Pumpkin seed compounds are studied for supporting healthy tone and function of the bladder and surrounding muscles.

Clinical trials

1
Pumpkin Seed and Urinary Health — Study
PubMed

Clinical study of pumpkin seed oil on urinary disorder. (Nishimura et al. 2014, Journal of Traditional and Complementary Medicine)

Adults with urinary symptoms.

Pumpkin seed oil improved urinary symptom measures, supporting its urinary and prostate positioning.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated.
Mild digestive upset is occasionally reported.
See a doctor for persistent urinary symptoms to rule out other causes.

Important Drug interactions

Blood pressure medication — pumpkin seed may have a mild additive effect; monitor.
Diuretics — possible additive effect.
Tell your doctor about prostate or urinary symptoms.

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Frequently asked questions about Cucurbidiol® (Pumpkin Seed Oil — Cucurbita)

What is Cucurbidiol?

Cucurbidiol® is a pumpkin seed (Cucurbita) oil ingredient, rich in phytosterols, zinc, and fatty acids traditionally used for prostate and urinary health. Pumpkin seed oil is studied for supporting comfortable urinary flow in men and is also used for hair support.

What is Cucurbidiol used for?

Cucurbidiol is researched primarily for Prostate Health, Men's Health, and Kidney/Urinary Tract. Pumpkin seed oil is studied for supporting comfortable urinary flow and easing the urinary symptoms linked to an aging prostate.

What is the recommended dosage of Cucurbidiol?

The clinically studied dose is Commonly around 500 mg to 1 g of pumpkin seed oil per day. Always follow the product label and check with a healthcare provider for personal advice.

Is Cucurbidiol safe, and does it have side effects?

For most healthy adults, Cucurbidiol is well tolerated at studied doses. Reported effects can include: Generally well-tolerated. Mild digestive upset is occasionally reported. It may also interact with some medications. Cucurbidiol is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does Cucurbidiol interact with any medications?

Possible interactions include: Blood pressure medication — pumpkin seed may have a mild additive effect; monitor. Diuretics — possible additive effect. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for Cucurbidiol?

NutraSmarts rates the evidence for Cucurbidiol as Limited (2 out of 5). It is backed by 1 clinical trial and 1 cited reference summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Nishimura M, Ohkawara T, Sato H, et al. Pumpkin Seed Oil Extracted From Cucurbita maxima Improves Urinary Disorder in Human Overactive Bladder. J Tradit Complement Med. 2014;4(1):72-4..PubMedUsed to support: Study supporting urinary and prostate benefit of pumpkin seed oil.