Chocamine® (Cocoa Extract — RFI)

Theobroma cacao
Evidence Level
Moderate
1 Clinical Trial
3 Documented Benefits
3/5 Evidence Score

Chocamine® is a patented cocoa (Theobroma cacao) extract from RFI, standardized for theobromine and cocoa polyphenols, delivering chocolate's active compounds without the sugar and fat. It is used for smooth, jitter-free energy and focus, while cocoa flavanols support healthy blood flow.

Studied Dose Commonly around 500 mg to 1.5 g of cocoa extract per day.
Active Compound Cocoa extract standardized for theobromine (more than 12%) with cocoa flavanols and a little caffeine.

Benefits

Smooth energy and focus

Theobromine, cocoa's main active, provides a gentle, longer-lasting lift in energy and focus with less of the jitter and crash of caffeine.

Cardiovascular support

Cocoa flavanols support healthy blood flow and blood pressure, as confirmed in a Cochrane review of cocoa.

Mood and cravings

Cocoa compounds are studied for supporting a positive mood and satisfying chocolate cravings.

Mechanism of action

1

Theobromine stimulation

Theobromine is a mild, long-acting relative of caffeine that supports energy and alertness with a smoother profile.

2

Flavanol nitric-oxide support

Cocoa flavanols boost nitric-oxide signaling in blood vessels, supporting healthy blood flow and blood pressure.

Clinical trials

1
Cocoa and Blood Pressure — Cochrane Review
PubMed

Cochrane systematic review of the effect of cocoa on blood pressure. (Ried et al. 2017, Cochrane Database of Systematic Reviews)

Adults across many trials.

Cocoa flavanols produced a small but significant reduction in blood pressure, supporting cocoa's cardiovascular positioning.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated.
Contains some caffeine and theobromine; can affect sleep if taken late.
Theobromine is toxic to dogs and cats; keep away from pets.

Important Drug interactions

Stimulant medications — possible additive effects; use caution.
Avoid taking late in the day if sensitive to stimulants.
Tell your doctor if pregnant or breastfeeding.

Frequently asked questions about Chocamine® (Cocoa Extract — RFI)

What is Chocamine?

Chocamine® is a patented cocoa (Theobroma cacao) extract from RFI, standardized for theobromine and cocoa polyphenols, delivering chocolate's active compounds without the sugar and fat. It is used for smooth, jitter-free energy and focus, while cocoa flavanols support healthy blood flow.

What is Chocamine used for?

Chocamine is researched primarily for Energy, Cognitive, and Cardiovascular. Theobromine, cocoa's main active, provides a gentle, longer-lasting lift in energy and focus with less of the jitter and crash of caffeine.

What is the recommended dosage of Chocamine?

The clinically studied dose is Commonly around 500 mg to 1.5 g of cocoa extract per day. Always follow the product label and check with a healthcare provider for personal advice.

Is Chocamine safe, and does it have side effects?

For most healthy adults, Chocamine is well tolerated at studied doses. Reported effects can include: Generally well-tolerated. Contains some caffeine and theobromine; can affect sleep if taken late. It may also interact with some medications. Chocamine is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does Chocamine interact with any medications?

Possible interactions include: Stimulant medications — possible additive effects; use caution. Avoid taking late in the day if sensitive to stimulants. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for Chocamine?

NutraSmarts rates the evidence for Chocamine as Moderate (3 out of 5). It is backed by 1 clinical trial and 1 cited reference summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Ried K, Fakler P, Stocks NP. Effect of cocoa on blood pressure. Cochrane Database Syst Rev. 2017;4(4):CD008893..PubMedUsed to support: Cochrane review supporting blood-pressure benefit of cocoa flavanols.