Cera-Q® (Silk Fibroin Peptides)

Evidence Level
Limited
1 Clinical Trial
3 Documented Benefits
2/5 Evidence Score

Cera-Q is a peptide ingredient derived from silk fibroin, the protein of silkworm cocoons, studied for supporting memory. Also known as BF-7, the silk fibroin enzymatic hydrolysate has been examined in a small placebo-controlled human study that reported dose-dependent memory improvement, though independent evidence is still limited.

Studied Dose About 400 to 600 mg of fibroin hydrolysate per day, in divided doses.
Active Compound Silk fibroin-derived peptides (hydrolyzed silk protein fragments), also called BF-7.

Benefits

Memory support

In a small placebo-controlled, double-blind human study, a silk fibroin enzymatic hydrolysate produced dose-dependent improvements in memory test scores in healthy adults, the basis for the ingredient's memory positioning.

Learning and recall

Study participants showed gains in learning, the number of words remembered, and retrieval efficiency, suggesting support for everyday memory performance.

Antioxidant neuroprotection

Silk fibroin peptides show antioxidant activity that may help protect brain cells from oxidative stress, as observed in laboratory and animal research.

Mechanism of action

1

Antioxidant brain protection

Silk fibroin peptides reduce reactive oxygen species and oxidative stress in brain tissue in laboratory and animal models, a proposed basis for their memory effects.

2

Neuroprotective support

In animal studies, the silk peptide BF-7 reduced ischemic brain-cell damage while supporting learning and memory, consistent with a neuroprotective mechanism.

Clinical trials

1
Silk Fibroin Hydrolysate and Memory — Human RCT
PubMed

Placebo-controlled, double-blind study of a silk fibroin enzymatic hydrolysate at 280 to 600 mg per day for 3 weeks. (Kang et al. 2018, Nutrients)

Healthy adults (average age about 55).

The fibroin hydrolysate produced dose-dependent improvements in memory quotient and related memory measures versus placebo, with no adverse effects reported.

Side effects and drug interactions

Common Potential side effects

GENERALLY WELL-TOLERATED — no adverse effects were reported in the human study.
Silk-allergic individuals should avoid this ingredient.
Discontinue if any unusual reaction occurs.

Important Drug interactions

Silk-allergic individuals should avoid this ingredient.
No major drug interactions are established.
Tell your doctor if pregnant, breastfeeding, or managing a condition.

Frequently asked questions about Cera-Q® (Silk Fibroin Peptides)

What is Cera-Q® (Silk Fibroin Peptides)?

Cera-Q is a peptide ingredient derived from silk fibroin, the protein of silkworm cocoons, studied for supporting memory. Also known as BF-7, the silk fibroin enzymatic hydrolysate has been examined in a small placebo-controlled human study that reported dose-dependent memory improvement, though independent evidence is…

What is the recommended dosage of Cera-Q® (Silk Fibroin Peptides)?

The clinically studied dose for Cera-Q® (Silk Fibroin Peptides) is About 400 to 600 mg of fibroin hydrolysate per day, in divided doses.. Always follow product labeling and consult a healthcare provider for personalized dosing recommendations.

What is Cera-Q® (Silk Fibroin Peptides) used for?

Cera-Q® (Silk Fibroin Peptides) is studied for memory support, learning and recall, antioxidant neuroprotection. In a small placebo-controlled, double-blind human study, a silk fibroin enzymatic hydrolysate produced dose-dependent improvements in memory test scores in healthy adults, the basis for the ingredient's memory positioning.

Are there side effects from taking Cera-Q® (Silk Fibroin Peptides)?

Reported potential side effects may include: GENERALLY WELL-TOLERATED — no adverse effects were reported in the human study. Silk-allergic individuals should avoid this ingredient. Always consult a healthcare provider before starting any new supplement, especially if you have underlying conditions or take medications.

Is Cera-Q® (Silk Fibroin Peptides) safe to take?

Whether Cera-Q® (Silk Fibroin Peptides) is safe depends on the dose, your overall health, and any medications you take. At studied doses, reported side effects can include: GENERALLY WELL-TOLERATED — no adverse effects were reported in the human study. It may also interact with certain medications. Cera-Q® (Silk Fibroin Peptides) is not suitable for everyone — consult a healthcare provider before use if you are pregnant or breastfeeding, have a medical condition, or take prescription medications.

References(2 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Kang YK, Lee BY, Bucci LR, Stohs SJ. Effect of a Fibroin Enzymatic Hydrolysate on Memory Improvement: A Placebo-Controlled, Double-Blind Study. Nutrients. 2018;10(2):233. doi: 10.3390/nu10020233..PubMedUsed to support: Human placebo-controlled study supporting memory benefit of silk fibroin hydrolysate.
  2. Noh Y, Ahn JH, Lee JW, et al. Brain Factor-7 improves learning and memory deficits and attenuates ischemic brain damage by reduction of ROS generation in stroke in vivo and in vitro. Lab Anim Res. 2020;36:24. doi: 10.1186/s42826-020-00057-x..PubMedUsed to support: Animal study supporting the neuroprotective and memory mechanism of silk fibroin peptide (BF-7).