Home Ingredients Centellory® (Gotu Kola Extract)
CognitiveMood & Mental Health

Centellory® (Gotu Kola Extract)

Centella asiatica
Evidence Level
Limited
1 Clinical Trial
3 Documented Benefits
2/5 Evidence Score

Centellory® is a standardized gotu kola (Centella asiatica) extract developed for memory and mood. Gotu kola is a revered herb in Ayurvedic and traditional Asian medicine, used to support the mind, and modern research finds it can support cognition and a positive mood, especially in older adults.

Studied Dose Commonly 250 to 750 mg of standardized extract per day.
Active Compound Standardized Centella asiatica extract concentrated for triterpenes (asiaticoside, madecassoside).

Benefits

Cognition and memory

In a randomized study in healthy older adults, Centella asiatica supported improvements in cognition, the basis for gotu kola's traditional brain-tonic use.

Supported by Trial 1

Mood support

The same research found positive effects on mood, supporting a calm, balanced mental state.

Supported by Trial 1

Circulatory and skin support

Gotu kola is also traditionally used to support healthy circulation and skin, linked to its triterpene compounds.

Supported by Trial 1

Mechanism of action

1

Triterpene neuroprotection

Gotu kola's asiaticoside and madecassoside support antioxidant defense and healthy nerve-cell signaling in the brain, a basis for its cognitive effects.

2

Microcirculation support

The triterpenes support healthy small-blood-vessel function and collagen, relevant to circulation and skin.

Clinical trials

1
Gotu Kola and Cognition/Mood — RCT
PubMed

Randomized study of Centella asiatica on cognition and mood in healthy elderly volunteers. (Wattanathorn et al. 2008, Journal of Ethnopharmacology)

Healthy elderly volunteers.

Centella asiatica positively modulated cognition and mood versus placebo.

Side effects and drug interactions

Common Potential side effects

GENERALLY WELL-TOLERATED — adverse effects are uncommon at normal doses.
Mild digestive upset is occasionally reported.
Discontinue if any unusual reaction occurs.

Important Drug interactions

Sedatives — possible additive calming effect; use caution.
Drugs metabolized by the liver — consult a doctor at high doses.
Tell your doctor if pregnant or breastfeeding.

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Frequently asked questions about Centellory® (Gotu Kola Extract)

What is Centellory® (Gotu Kola Extract)?

Centellory® is a standardized gotu kola (Centella asiatica) extract developed for memory and mood. Gotu kola is a revered herb in Ayurvedic and traditional Asian medicine, used to support the mind, and modern research finds it can support cognition and a positive mood, especially in older adults.

What is the recommended dosage of Centellory® (Gotu Kola Extract)?

The clinically studied dose for Centellory® (Gotu Kola Extract) is Commonly 250 to 750 mg of standardized extract per day.. Always follow product labeling and consult a healthcare provider for personalized dosing recommendations.

What is Centellory® (Gotu Kola Extract) used for?

Centellory® (Gotu Kola Extract) is studied for cognition and memory, mood support, circulatory and skin support. In a randomized study in healthy older adults, Centella asiatica supported improvements in cognition, the basis for gotu kola's traditional brain-tonic use.

Are there side effects from taking Centellory® (Gotu Kola Extract)?

Reported potential side effects may include: GENERALLY WELL-TOLERATED — adverse effects are uncommon at normal doses. Mild digestive upset is occasionally reported. Always consult a healthcare provider before starting any new supplement, especially if you have underlying conditions or take medications.

Is Centellory® (Gotu Kola Extract) safe to take?

Whether Centellory® (Gotu Kola Extract) is safe depends on the dose, your overall health, and any medications you take. At studied doses, reported side effects can include: GENERALLY WELL-TOLERATED — adverse effects are uncommon at normal doses. It may also interact with certain medications. Centellory® (Gotu Kola Extract) is not suitable for everyone — consult a healthcare provider before use if you are pregnant or breastfeeding, have a medical condition, or take prescription medications.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Wattanathorn J, Mator L, Muchimapura S, et al. Positive modulation of cognition and mood in the healthy elderly volunteer following the administration of Centella asiatica. J Ethnopharmacol. 2008;116(2):325-32..PubMedUsed to support: RCT supporting cognition and mood benefit of gotu kola.