Home Ingredients Centellory® (Gotu Kola Extract)
CognitiveMood & Mental Health

Centellory® (Gotu Kola Extract)

Centella asiatica
Evidence Level
Limited
1 Clinical Trial
3 Documented Benefits
2/5 Evidence Score

Centellory® is a standardized gotu kola (Centella asiatica) extract developed for memory and mood. Gotu kola is a revered herb in Ayurvedic and traditional Asian medicine, used to support the mind, and modern research finds it can support cognition and a positive mood, especially in older adults.

Studied Dose Commonly 250 to 750 mg of standardized extract per day.
Active Compound Standardized Centella asiatica extract concentrated for triterpenes (asiaticoside, madecassoside).

Benefits

Cognition and memory

In a randomized study in healthy older adults, Centella asiatica supported improvements in cognition, the basis for gotu kola's traditional brain-tonic use.

Supported by Trial 1

Mood support

The same research found positive effects on mood, supporting a calm, balanced mental state.

Supported by Trial 1

Circulatory and skin support

Gotu kola is also traditionally used to support healthy circulation and skin, linked to its triterpene compounds.

Supported by Trial 1

Mechanism of action

1

Triterpene neuroprotection

Gotu kola's asiaticoside and madecassoside support antioxidant defense and healthy nerve-cell signaling in the brain, a basis for its cognitive effects.

2

Microcirculation support

The triterpenes support healthy small-blood-vessel function and collagen, relevant to circulation and skin.

Clinical trials

1
Gotu Kola and Cognition/Mood — RCT
PubMed

Randomized study of Centella asiatica on cognition and mood in healthy elderly volunteers. (Wattanathorn et al. 2008, Journal of Ethnopharmacology)

Healthy elderly volunteers.

Centella asiatica positively modulated cognition and mood versus placebo.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated — adverse effects are uncommon at normal doses.
Mild digestive upset is occasionally reported.
Discontinue if any unusual reaction occurs.

Important Drug interactions

Sedatives — possible additive calming effect; use caution.
Drugs metabolized by the liver — consult a doctor at high doses.
Tell your doctor if pregnant or breastfeeding.

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Frequently asked questions about Centellory® (Gotu Kola Extract)

What is Centellory?

Centellory® is a standardized gotu kola (Centella asiatica) extract developed for memory and mood. Gotu kola is a revered herb in Ayurvedic and traditional Asian medicine, used to support the mind, and modern research finds it can support cognition and a positive mood, especially in older adults.

What is Centellory used for?

Centellory is researched primarily for Cognitive and Mood & Mental Health. In a randomized study in healthy older adults, Centella asiatica supported improvements in cognition, the basis for gotu kola's traditional brain-tonic use.

What is the recommended dosage of Centellory?

The clinically studied dose is Commonly 250 to 750 mg of standardized extract per day. Always follow the product label and check with a healthcare provider for personal advice.

Is Centellory safe, and does it have side effects?

For most healthy adults, Centellory is well tolerated at studied doses. Reported effects can include: Generally well-tolerated — adverse effects are uncommon at normal doses. Mild digestive upset is occasionally reported. It may also interact with some medications. Centellory is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does Centellory interact with any medications?

Possible interactions include: Sedatives — possible additive calming effect; use caution. Drugs metabolized by the liver — consult a doctor at high doses. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for Centellory?

NutraSmarts rates the evidence for Centellory as Limited (2 out of 5). It is backed by 1 clinical trial and 1 cited reference summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Wattanathorn J, Mator L, Muchimapura S, et al. Positive modulation of cognition and mood in the healthy elderly volunteer following the administration of Centella asiatica. J Ethnopharmacol. 2008;116(2):325-32..PubMedUsed to support: RCT supporting cognition and mood benefit of gotu kola.