Home Ingredients BiAloe® (Aloe Vera Polysaccharides)
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BiAloe® (Aloe Vera Polysaccharides)

Aloe barbadensis
Evidence Level
Preliminary
0 Clinical Trials
3 Documented Benefits
1/5 Evidence Score

BiAloe® is an aloe vera (Aloe barbadensis) ingredient concentrated for the long-chain acemannan polysaccharides thought to drive aloe's benefits. Aloe is traditionally used for digestive and skin support. Independent published clinical data for this specific ingredient are limited.

Studied Dose Commonly a few hundred milligrams per day.
Active Compound Aloe vera (Aloe barbadensis) inner-leaf extract concentrated for acemannan polysaccharides.

Benefits

Digestive support

Aloe vera inner leaf is traditionally used to soothe the digestive tract and support comfortable digestion.

Skin support

Aloe polysaccharides are studied for supporting skin hydration and healing, both topically and from within.

Limited-evidence note

Aloe has a long traditional history, but dedicated published clinical trials for this specific concentrated ingredient are limited.

Mechanism of action

1

Acemannan polysaccharides

Aloe's long-chain acemannan polysaccharides are thought to support the gut lining, immune cells, and skin tissue.

2

Soothing and hydrating action

Aloe compounds provide soothing, hydrating, and antioxidant support to skin and the digestive tract.

Clinical trials

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated — use inner-leaf (decolorized) aloe.
Whole-leaf aloe with aloin can act as a harsh laxative; avoid.
Discontinue if digestive upset occurs.

Important Drug interactions

Diabetes medication — aloe may lower blood sugar; monitor.
Laxative-type aloe can affect potassium and some medications.
Tell your doctor if pregnant or breastfeeding.

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Frequently asked questions about BiAloe® (Aloe Vera Polysaccharides)

What is BiAloe?

BiAloe® is an aloe vera (Aloe barbadensis) ingredient concentrated for the long-chain acemannan polysaccharides thought to drive aloe's benefits. Aloe is traditionally used for digestive and skin support. Independent published clinical data for this specific ingredient are limited.

What is BiAloe used for?

BiAloe is researched primarily for Gut Health, Hair, Skin & Nails, and Immune Support. Aloe vera inner leaf is traditionally used to soothe the digestive tract and support comfortable digestion.

What is the recommended dosage of BiAloe?

The clinically studied dose is Commonly a few hundred milligrams per day. Always follow the product label and check with a healthcare provider for personal advice.

Is BiAloe safe, and does it have side effects?

For most healthy adults, BiAloe is well tolerated at studied doses. Reported effects can include: Generally well-tolerated — use inner-leaf (decolorized) aloe. Whole-leaf aloe with aloin can act as a harsh laxative; avoid. It may also interact with some medications. BiAloe is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does BiAloe interact with any medications?

Possible interactions include: Diabetes medication — aloe may lower blood sugar; monitor. Laxative-type aloe can affect potassium and some medications. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for BiAloe?

NutraSmarts rates the evidence for BiAloe as Preliminary (1 out of 5). It is backed by 2 cited references summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(2 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Ahluwalia B, Magnusson MK, Böhn L, Störsrud S, Larsson F, Öhman L, Simrén M Aloe barbadensis Mill. extract improves symptoms in IBS patients with diarrhoea: post hoc analysis of two randomized double-blind controlled studies Therapeutic Advances in Gastroenterology. 2021;14:17562848211048133. doi:10.1177/17562848211048133.PubMedUsed to support: Post-hoc analysis of two human RCTs (n=213 IBS patients) showing Aloe barbadensis extract reduced overall symptom severity in diarrhea-predominant IBS patients (58% responders vs. 30% placebo, p=0.02); supports the digestive-support benefit of aloe vera polysaccharides relevant to BiAloe®. Evidence is for an Aloe barbadensis extract (AVH200®), not the BiAloe® brand specifically.
  2. Cho S, Lee S, Lee MJ, Lee DH, Won CH, Kim SM, Chung JH Dietary Aloe Vera Supplementation Improves Facial Wrinkles and Elasticity and It Increases the Type I Procollagen Gene Expression in Human Skin in vivo Annals of Dermatology. 2009;21(1):6-11. doi:10.5021/ad.2009.21.1.6.PubMedUsed to support: Human clinical trial in 30 women over 45 showing oral aloe vera supplementation (1,200 mg/d and 3,600 mg/d for 90 days) significantly improved facial wrinkles and elasticity and upregulated type I procollagen gene expression in skin; supports the skin-support benefit attributed to aloe vera polysaccharides relevant to BiAloe®. Evidence is for dietary aloe vera supplement, not the BiAloe® brand specifically.