Benolea® (Olive Leaf Extract — EFLA 943)

Olea europaea
Evidence Level
Moderate
1 Clinical Trial
3 Documented Benefits
3/5 Evidence Score

Benolea® is a standardized olive leaf (Olea europaea) extract, known by the EFLA 943 designation, concentrated for oleuropein. Olive leaf polyphenols are studied for supporting healthy blood pressure and broader cardiovascular and metabolic markers as part of a Mediterranean-style approach to heart health.

Studied Dose Commonly around 500 to 1000 mg per day.
Active Compound Standardized olive leaf extract (EFLA 943) concentrated for oleuropein and related polyphenols.

Benefits

Cardiovascular support

In a randomized placebo-controlled trial, olive leaf extract supported improvements in cardiovascular health markers, consistent with its heart-health positioning.

Healthy blood pressure

Olive leaf polyphenols are studied for supporting blood pressure already within a healthy range.

Antioxidant and metabolic support

Oleuropein is a strong antioxidant that also supports healthy blood-sugar and lipid markers.

Mechanism of action

1

Oleuropein activity

Oleuropein and its metabolite hydroxytyrosol support healthy blood-vessel function and antioxidant defense, mechanisms tied to blood-pressure and vascular health.

2

Nitric-oxide support

Olive polyphenols help maintain the nitric-oxide signaling that keeps blood vessels relaxed and flexible.

Clinical trials

1
Olive Leaf Extract and Cardiovascular Markers — RCT
PubMed

Randomized placebo-controlled clinical trial of olive leaf extract on cardiovascular health markers. (Stevens et al. 2021, European Journal of Nutrition)

Adults.

Olive leaf extract supported improvements in cardiovascular health markers versus placebo.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated — adverse effects are uncommon at normal doses.
Mild digestive upset is occasionally reported.
Discontinue if any unusual reaction occurs.

Important Drug interactions

Blood pressure medication — olive leaf may add to blood-pressure lowering; monitor.
Diabetes medication — may modestly lower blood sugar; monitor.
Tell your doctor if you take cardiovascular medication.

Frequently asked questions about Benolea® (Olive Leaf Extract — EFLA 943)

What is Benolea?

Benolea® is a standardized olive leaf (Olea europaea) extract, known by the EFLA 943 designation, concentrated for oleuropein. Olive leaf polyphenols are studied for supporting healthy blood pressure and broader cardiovascular and metabolic markers as part of a Mediterranean-style approach to heart health.

What is Benolea used for?

Benolea is researched primarily for Cardiovascular. In a randomized placebo-controlled trial, olive leaf extract supported improvements in cardiovascular health markers, consistent with its heart-health positioning.

What is the recommended dosage of Benolea?

The clinically studied dose is Commonly around 500 to 1000 mg per day. Always follow the product label and check with a healthcare provider for personal advice.

Is Benolea safe, and does it have side effects?

For most healthy adults, Benolea is well tolerated at studied doses. Reported effects can include: Generally well-tolerated — adverse effects are uncommon at normal doses. Mild digestive upset is occasionally reported. It may also interact with some medications. Benolea is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does Benolea interact with any medications?

Possible interactions include: Blood pressure medication — olive leaf may add to blood-pressure lowering; monitor. Diabetes medication — may modestly lower blood sugar; monitor. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for Benolea?

NutraSmarts rates the evidence for Benolea as Moderate (3 out of 5). It is backed by 1 clinical trial and 1 cited reference summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Stevens Y, Winkens B, Jonkers D, et al. The effect of olive leaf extract on cardiovascular health markers: a randomized placebo-controlled clinical trial. Eur J Nutr. 2021;60(4):2111-2120..PubMedUsed to support: RCT supporting cardiovascular-marker benefit of olive leaf extract.