BeneGut® (Perilla Extract — Vital Solutions)

Perilla frutescens
Evidence Level
Moderate
1 Clinical Trial
3 Documented Benefits
3/5 Evidence Score

BeneGut® is a standardized perilla (Perilla frutescens) leaf extract from Vital Solutions, developed for digestive comfort. Perilla is rich in rosmarinic acid and other polyphenols, and a clinical study found the extract eased everyday gastrointestinal discomfort such as bloating, rumbling, and feelings of fullness.

Studied Dose Around 150 to 300 mg of extract per day.
Active Compound Standardized perilla leaf extract concentrated for rosmarinic acid and related polyphenols.

Benefits

Digestive comfort

In a randomized placebo-controlled study, perilla extract improved everyday gastrointestinal discomfort, including bloating, rumbling, and a feeling of fullness.

Gut-calming support

Perilla polyphenols are studied for supporting a calm, comfortable gut and reducing the bothersome sensations of a sensitive digestive system.

Antioxidant gut support

Rosmarinic acid provides antioxidant and soothing support to the digestive lining.

Mechanism of action

1

Anti-inflammatory polyphenols

Perilla's rosmarinic acid and luteolin calm inflammatory and spasmodic signaling in the gut, easing discomfort and bloating.

2

Gut-motility support

The extract is thought to support more comfortable, regular gut motility and reduced gas-related distension.

Clinical trials

1
Perilla Extract and GI Discomfort — RCT
PubMed

Randomized placebo-controlled double-blind human pilot study of perilla extract on gastrointestinal discomfort. (Buchwald-Werner et al. 2014, BMC Complementary and Alternative Medicine)

Adults with gastrointestinal discomfort.

Perilla extract improved measures of bloating, rumbling, and fullness versus placebo.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated — adverse effects are uncommon at normal doses.
Mild digestive upset is occasionally reported.
Discontinue if any unusual reaction occurs.

Important Drug interactions

No major drug interactions are established for this ingredient.
Tell your doctor about all supplements if you take prescription medication.
Use caution if pregnant, breastfeeding, or managing a health condition.

Frequently asked questions about BeneGut® (Perilla Extract — Vital Solutions)

What is BeneGut?

BeneGut® is a standardized perilla (Perilla frutescens) leaf extract from Vital Solutions, developed for digestive comfort. Perilla is rich in rosmarinic acid and other polyphenols, and a clinical study found the extract eased everyday gastrointestinal discomfort such as bloating, rumbling, and feelings of fullness.

What is BeneGut used for?

BeneGut is researched primarily for Gut Health. In a randomized placebo-controlled study, perilla extract improved everyday gastrointestinal discomfort, including bloating, rumbling, and a feeling of fullness.

What is the recommended dosage of BeneGut?

The clinically studied dose is Around 150 to 300 mg of extract per day. Always follow the product label and check with a healthcare provider for personal advice.

Is BeneGut safe, and does it have side effects?

For most healthy adults, BeneGut is well tolerated at studied doses. Reported effects can include: Generally well-tolerated — adverse effects are uncommon at normal doses. Mild digestive upset is occasionally reported. It may also interact with some medications. BeneGut is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does BeneGut interact with any medications?

Possible interactions include: No major drug interactions are established for this ingredient. Tell your doctor about all supplements if you take prescription medication. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for BeneGut?

NutraSmarts rates the evidence for BeneGut as Moderate (3 out of 5). It is backed by 1 clinical trial and 1 cited reference summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Buchwald-Werner S, Fujii H, Reule C, et al. Perilla extract improves gastrointestinal discomfort in a randomized placebo controlled double blind human pilot study. BMC Complement Altern Med. 2014;14:173..PubMedUsed to support: RCT supporting digestive-comfort benefit of perilla extract.