Ayuric® (Terminalia bellirica Extract for Uric Acid — Natreon)

Terminalia bellirica
Evidence Level
Moderate
1 Clinical Trial
3 Documented Benefits
3/5 Evidence Score

Ayuric® is a standardized extract of the fruit of Terminalia bellirica (bibhitaki), a tree fruit used in Ayurveda. It is studied for supporting healthy uric acid levels by inhibiting xanthine oxidase, the same enzyme targeted by conventional uric-acid drugs, making it a natural option for joint and uric-acid support.

Studied Dose Commonly 500 mg twice daily (about 1 g per day).
Active Compound Standardized Terminalia bellirica fruit extract, a tannin-rich natural xanthine oxidase inhibitor.

Benefits

Healthy uric acid levels

In a randomized controlled trial, Terminalia bellirica extract lowered elevated uric acid levels, supporting its positioning for uric-acid and gout-related joint comfort.

Joint comfort

By lowering uric acid, the extract supports the joints against the discomfort linked to uric-acid buildup.

Antioxidant support

The tannin-rich extract provides antioxidant activity that complements its uric-acid effect.

Mechanism of action

1

Xanthine oxidase inhibition

Terminalia bellirica compounds inhibit xanthine oxidase, the enzyme that produces uric acid, reducing uric-acid synthesis.

2

Antioxidant action

The extract's tannins and gallic acid scavenge free radicals, supporting overall metabolic health.

Clinical trials

1
Terminalia bellirica and Uric Acid — RCT
PubMed

Randomized, double-blind, positive-controlled dose-response clinical study of Terminalia bellirica extract on uric acid. (Pingali et al. 2020, BMC Complementary Medicine and Therapies)

Adults with elevated uric acid.

Terminalia bellirica extract produced dose-dependent reductions in serum uric acid versus control.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated — digestive symptoms are most common.
Mild stomach upset is occasionally reported.
Discontinue if any unusual reaction occurs.

Important Drug interactions

Uric-acid medication (allopurinol, febuxostat) — possible additive effect; consult a doctor.
Diabetes medication — monitor blood sugar.
Tell your doctor if you have gout or kidney disease.

Frequently asked questions about Ayuric® (Terminalia bellirica Extract for Uric Acid — Natreon)

What is Ayuric?

Ayuric® is a standardized extract of the fruit of Terminalia bellirica (bibhitaki), a tree fruit used in Ayurveda. It is studied for supporting healthy uric acid levels by inhibiting xanthine oxidase, the same enzyme targeted by conventional uric-acid drugs, making it a natural option for joint and uric-acid support.

What is Ayuric used for?

Ayuric is researched primarily for Joint Health and Kidney/Urinary Tract. In a randomized controlled trial, Terminalia bellirica extract lowered elevated uric acid levels, supporting its positioning for uric-acid and gout-related joint comfort.

What is the recommended dosage of Ayuric?

The clinically studied dose is Commonly 500 mg twice daily (about 1 g per day). Always follow the product label and check with a healthcare provider for personal advice.

Is Ayuric safe, and does it have side effects?

For most healthy adults, Ayuric is well tolerated at studied doses. Reported effects can include: Generally well-tolerated — digestive symptoms are most common. Mild stomach upset is occasionally reported. It may also interact with some medications. Ayuric is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does Ayuric interact with any medications?

Possible interactions include: Uric-acid medication (allopurinol, febuxostat) — possible additive effect; consult a doctor. Diabetes medication — monitor blood sugar. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for Ayuric?

NutraSmarts rates the evidence for Ayuric as Moderate (3 out of 5). It is backed by 1 clinical trial and 1 cited reference summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Pingali U, Nutalapati C, Koilagundla N, et al. A randomized, double-blind, positive-controlled, prospective, dose-response clinical study of the efficacy and tolerability of a standardized aqueous extract of Terminalia bellerica in lowering uric acid. BMC Complement Med Ther. 2020;20(1):281..PubMedUsed to support: RCT supporting uric-acid-lowering benefit of Terminalia bellirica.