Home Ingredients ActivAloe® (Standardized Aloe Vera — Aloecorp)
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ActivAloe® (Standardized Aloe Vera — Aloecorp)

Aloe barbadensis
Evidence Level
Limited
0 Clinical Trials
3 Documented Benefits
2/5 Evidence Score

ActivAloe® is a standardized aloe vera (Aloe barbadensis) from Aloecorp, processed to preserve its active polysaccharides such as acemannan. Aloe vera is taken to support digestive comfort and skin health, and ActivAloe is standardized for consistent polysaccharide content. Dedicated published data for this specific brand are limited.

Studied Dose Per the product specification.
Active Compound Aloe vera (Aloe barbadensis) inner-leaf concentrate standardized for polysaccharides (including acemannan).

Benefits

Digestive comfort

Aloe vera inner-leaf is traditionally used to soothe the digestive tract and support comfortable digestion.

Skin support

Aloe polysaccharides support skin hydration and a healthy skin barrier, whether taken internally or applied topically.

Limited-evidence note

Aloe vera has supportive research as a plant, but dedicated published clinical data for this specific standardized brand are limited.

Mechanism of action

1

Polysaccharide soothing action

Aloe's acemannan and related polysaccharides form a soothing, moisture-retaining layer and support the gut and skin barrier.

2

Antioxidant plant compounds

Aloe contains antioxidant polyphenols and vitamins that help protect cells from oxidative stress.

Clinical trials

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated — use decolorized, low-aloin inner-leaf products.
Whole-leaf aloe with aloin can have a laxative effect; choose purified forms.
Discontinue if you experience cramping or diarrhea.

Important Drug interactions

Diabetes medication — aloe may lower blood sugar; monitor.
Laxative effect (aloin forms) can affect potassium and some drugs; choose purified aloe.
Tell your doctor if pregnant or breastfeeding.

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Frequently asked questions about ActivAloe® (Standardized Aloe Vera — Aloecorp)

What is ActivAloe?

ActivAloe® is a standardized aloe vera (Aloe barbadensis) from Aloecorp, processed to preserve its active polysaccharides such as acemannan. Aloe vera is taken to support digestive comfort and skin health, and ActivAloe is standardized for consistent polysaccharide content.

What is ActivAloe used for?

ActivAloe is researched primarily for Gut Health and Hair, Skin & Nails. Aloe vera inner-leaf is traditionally used to soothe the digestive tract and support comfortable digestion.

What is the recommended dosage of ActivAloe?

The clinically studied dose is Per the product specification. Always follow the product label and check with a healthcare provider for personal advice.

Is ActivAloe safe, and does it have side effects?

For most healthy adults, ActivAloe is well tolerated at studied doses. Reported effects can include: Generally well-tolerated — use decolorized, low-aloin inner-leaf products. Whole-leaf aloe with aloin can have a laxative effect; choose purified forms. It may also interact with some medications. ActivAloe is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does ActivAloe interact with any medications?

Possible interactions include: Diabetes medication — aloe may lower blood sugar; monitor. Laxative effect (aloin forms) can affect potassium and some drugs; choose purified aloe. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for ActivAloe?

NutraSmarts rates the evidence for ActivAloe as Limited (2 out of 5). It is backed by 4 cited references summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(4 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Sánchez M, González-Burgos E, Iglesias I, Gómez-Serranillos MP Pharmacological Update Properties of Aloe Vera and its Major Active Constituents Molecules. 2020;25(6):1324. doi:10.3390/molecules25061324.PubMedUsed to support: Comprehensive review of aloe vera pharmacology including gastrointestinal effects (digestive comfort), skin wound-healing, and anti-inflammatory activity of key constituents including acemannan polysaccharides. Supports the aloe vera component of ActivAloe®, not the brand specifically.
  2. Liu C, Cui Y, Pi F, Cheng Y, Guo Y, Qian H Extraction, Purification, Structural Characteristics, Biological Activities and Pharmacological Applications of Acemannan, a Polysaccharide from Aloe vera: A Review Molecules. 2019;24(8):1554. doi:10.3390/molecules24081554.PubMedUsed to support: Review of acemannan — the key standardized polysaccharide in aloe vera — documenting its biological activities including immunomodulation, wound healing, and gastrointestinal effects. Supports the acemannan standardization claim of ActivAloe®; evidence is for the compound, not the brand.
  3. Størsrud S, Pontén I, Simrén M A Pilot Study of the Effect of Aloe barbadensis Mill. Extract (AVH200®) in Patients with Irritable Bowel Syndrome: a Randomized, Double-Blind, Placebo-Controlled Study Journal of Gastrointestinal and Liver Diseases. 2015;24(3):275-80. doi:10.15403/jgld.2014.1121.243.sst.PubMedUsed to support: Human RCT showing aloe vera extract (standardized Aloe barbadensis) reduced abdominal pain and discomfort in IBS patients compared to placebo. Supports digestive comfort benefit of aloe vera; evidence is for a different standardized aloe extract brand (AVH200®), not ActivAloe® specifically.
  4. Sahebnasagh A, Ghasemi A, Akbari J, Alipour A, Lashkardoost H, Ala S, Salehifar E Successful Treatment of Acute Radiation Proctitis with Aloe Vera: A Preliminary Randomized Controlled Clinical Trial Journal of Alternative and Complementary Medicine. 2017;23(11):858-865. doi:10.1089/acm.2017.0047.PubMedUsed to support: Human RCT demonstrating aloe vera gel significantly reduced rectal pain, diarrhea, and urgency in radiation proctitis, supporting aloe vera's gut-soothing effects in a clinical disease context (radiation proctitis). Evidence is for aloe vera gel generally, not ActivAloe® specifically, and does not indicate that ActivAloe treats any disease.