Deficiency Guide

Vitamin C deficiency

Symptoms, at-risk groups, and clinical context for vitamin c deficiency. Sourced from NIH Office of Dietary Supplements and StatPearls.

Severe vitamin C deficiency causes scurvy, whose signs can appear within about a month of getting less than about 10 mg a day. Scurvy is rare in developed countries but still occurs in people with very limited diets, and it can be fatal if untreated. Intakes below the RDA but above that level are more likely in people who smoke, infants fed evaporated or boiled cow's milk, people with limited diets and people with malabsorption or certain chronic diseases.

Common symptoms

  • Fatigue and feeling unwell
  • Inflamed, swollen or bleeding gums
  • Small red or purple spots on the skin and easy bruising
  • Joint pain
  • Poor wound healing
  • Rough, thickened skin
  • Corkscrew-shaped body hairs
  • Loose teeth or tooth loss (advanced)
  • Iron deficiency anemia from bleeding and poor iron absorption
  • Depression

At-risk groups

  • People who smoke (they need 35 mg more a day) and people exposed to secondhand smoke
  • Infants fed evaporated or boiled cow's milk
  • People with very limited diets, including some older adults on low incomes who prepare their own food
  • People with alcohol or drug use disorders
  • People with severe intestinal malabsorption or cachexia
  • People with end-stage kidney disease on long-term hemodialysis
When to see a doctorEasy bruising, bleeding gums and slow wound healing in someone with a limited diet should be checked by a doctor. Vitamin C deficiency is treatable, and a blood test of vitamin C can help confirm it. Without treatment, scurvy can be fatal.
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Related deficiencies

Nutrients with overlapping symptoms — useful when investigating an unclear clinical picture.