The 5 Best Red Yeast Rice Supplements for Heart & Cholesterol Health in 2025
- Vlad Salamakha
- Jun 28
- 5 min read
Updated: 16 hours ago
What Is Red Yeast Rice?
Red Yeast Rice is a traditional Chinese ingredient made by fermenting white rice with a specific type of yeast called Monascus purpureus. This fermentation process produces compounds known as monacolins, especially monacolin K, which is chemically identical to the active ingredient in the prescription cholesterol-lowering drug lovastatin.
Used for centuries in Asian cuisine and medicine, Red Yeast Rice has gained widespread popularity in the West as a natural supplement for supporting healthy cholesterol levels, improving heart health, and maintaining overall cardiovascular function.
What sets it apart is its ability to help lower LDL ("bad") cholesterol and total cholesterol without the need for synthetic statins. However, the effectiveness and safety of Red Yeast Rice can vary widely between products, depending on how they are made and the concentrations of active ingredients.
Top 5 Red Yeast Rice Supplements of 2025:
1. Weider Red Yest Rice Plus
Key Features: 1200mg of Red Yeast Rice Powder per Tablet
Why it made it to the list: High doses of Red Yeast Rice at 1200mg and Plant Phytosterols at 850mg with Microalgae (Haematococcus pluvialis) Astaxanthin at 1mg.
Price: $21.99
Pros:
✅ High Potency: Delivers 1200 mg of red yeast rice and 850mg of Phytosterols per serving for a more concentrated dose.
✅ Amazing Price: Only $21.99 for 240 tablets or 120 days.
✅ Astaxanthin: Contains Haematococcus pluvialis supplying Astaxanthin as an antioxidant for heart support.
Cons:
❌Large tablet: Might be hard for some to swallow.
❌Lots of Excipients and Fillers: Contains 500mg or more of excipients to make a good tablet including calcium carbonate and microcrystalline cellulose.
❌Slow Disintegration: Potential for slow disintegration times due to high level of phytosterols.
❌Contains Soy: Phytosterols is derived from Soy, which is an allergen.
2. Natures Craft Red Yeast Rice and CoQ10
Key Features: Contains 1200mg of Red Yeast Rice and 100mg of CoQ10
Why It Made the List: Qunol Red Yeast Rice + CoQ10 is a heart health supplement that combines 1,200 mg of red yeast rice with 100 mg of CoQ10 per serving to support healthy cholesterol levels and cardiovascular function. Formulated to be citrinin-free, it offers a safer alternative to traditional red yeast rice products, while the added CoQ10 helps replenish levels that may be depleted by statin-like compounds. This supplement is designed for individuals seeking a natural way to manage heart health, especially those looking for dual-action support. Produced by a trusted brand, it contains no artificial colors or flavors, though it may not be suitable for vegetarians or those with sensitivities to statin effects.
Price: $17.59 Sale Price ($25.00 Original Price)
Pros:
✅ Dual support for heart health: Combines Red Yeast Rice (RYR) and CoQ10, which may help support healthy cholesterol levels and overall cardiovascular function.
✅ High potency: Delivers 1200 mg of Red Yeast Rice and 100 mg of CoQ10 per serving, offering strong therapeutic doses.
✅Easier to swallow: Capsules are generally easier to swallow than tablets.
✅ Great Price: Only $17.95 for a 60 day supply for a total of 120 capsules.
✅ Citrinin-Free: Tested to be free of citrinin, a potentially harmful byproduct of red yeast fermentation, increasing safety.
Cons:
❌ Low dose of CoQ10 at 100mg. Clinical trials show doses of 300mg+ for heart health.
❌ Contains fillers/excipients: Contains microcrystalline cellulose, silicon dioxide and magnesium stearate which are avoided by some people.
3. Thorne Red Yeast Rice + CoQ10
Key Features: One capsule dose of 600mg of Red Yeast Rice and 15mg of CoQ10.
Why It Made the List: Thorne Red Yeast Rice + CoQ10 is a premium cardiovascular support supplement that blends 600 mg of red yeast rice with 30 mg of CoQ10 per capsule to promote healthy cholesterol levels and heart function. Made by a trusted brand known for rigorous quality testing, it is free from citrinin and common allergens like gluten, soy, and dairy. Ideal for those seeking natural cholesterol support with added antioxidant benefits, this formula supports heart health without compromising purity or safety.
Price: $42.00
Pros:
✅ Dual support for heart health: Combines Red Yeast Rice (RYR) and CoQ10, which may help support healthy cholesterol levels and overall cardiovascular function.
✅ No fillers: Includes only leucine to anti-caking and lubrication on the encapsulation machine.
✅ Citrinin-Free: Tested to be free of citrinin, a potentially harmful byproduct of red yeast fermentation, increasing safety.
Cons:
❌ Low dose of CoQ10 at 15mg. Clinical trials show doses of 300mg+ for heart health.
❌ Expensive: Premium price point may not suit all budgets
Very expensive compared to other brands.
4. Purely Holistic Red Yeast Rice with CoQ10 and Niacin
Key Features: Red Yeast Rice, CoQ10 and Niacin as Inositol Hexanicotinate.
Why It Made the List: Purely Holistic Red Yeast Rice with Niacin delivers 1,200 mg of red yeast rice along with 35 mg of niacin per serving to help support healthy cholesterol levels and overall cardiovascular wellness. This vegetarian-friendly supplement is made without gluten, non-GMO ingredients, or artificial flavors, making it a clean option for daily heart support. With added niacin, it enhances lipid metabolism benefits while maintaining a simple, straightforward formula.
Price: $22.97
Pros:
✅ Dual support for heart health: Combines red yeast rice and niacin for enhanced cholesterol support
✅ High potency: With 1,200 mg of red yeast rice per serving
✅Easier to swallow: Capsules are generally easier to swallow than tablets.
✅ Citrinin-Free: Tested to be free of citrinin, a potentially harmful byproduct of red yeast fermentation, increasing safety.
Cons:
❌ Low dose of Inositol Hexanicotinate: Most clinical trials are at 500mg to 4000mg a day.
❌ California Prop 65 warning: Prop 65 warning most likely due to high heavy metal content.
❌ Low dose of CoQ10 at 60mg. Clinical trials show doses of 300mg+ for heart health.
5. Carlyle Red Yeast Rice Capsules
Key Features: 1800mg of Red Yeast Rice powder
Why It Made the List: Carlyle Red Yeast Rice provides 1,200 mg of red yeast rice per serving, offering a traditional herbal approach to supporting healthy cholesterol levels and cardiovascular wellness. This supplement is made with non-GMO ingredients, is gluten-free, and comes in easy-to-swallow quick-release capsules. Backed by lab-tested quality and manufactured in the USA, it’s a reliable and budget-friendly choice for heart health support.
Price: $17.99
Pros:
✅ High potency: With 1,800 mg of red yeast rice per serving
✅ Great Price: Only $17.99 for a 83 day supply for a total of 250 capsules.
✅Easier to swallow: Capsules are generally easier to swallow than tablets.
Cons:
❌ Citrinin Content not Specified : Doesn’t specify citrinin-free status, which some users may find concerning
❌ No supporting ingredients: No added CoQ10, niacin or other heart health ingredients which may be beneficial when taking red yeast rice
❌ Gelatin Capsule: Most likely made from pig gelatin.
Final Thoughts
Red Yeast Rice can be a powerful natural option for maintaining healthy cholesterol levels when used appropriately and with guidance from a healthcare professional.
When choosing a supplement, always prioritize purity, reliable sourcing, and clinical-grade potency. The products listed above are among the most trusted options available in 2025 and can help support your heart health journey naturally.
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